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A 3-in-1 Polymeric Micelle Nanocontainer For Poorly Water-Soluble Drugs

Poly(ethylene glycol)-block-poly(d,l lactic acid) (PEG-b-PLA) micelles have a proven capacity for drug solubilization and have entered phase III clinical trials as a substitute for Cremophor EL in the delivery of paclitaxel in cancer therapy. PEG-b-PLA is less toxic than Cremophor EL, enabling a dou...

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Detalles Bibliográficos
Publicado en:Mol Pharm
Autores principales: Shin, Ho Chul, Alani, Adam WG., Cho, Hyunah, Bae, Younsoo, Kolesar, Jill M., Kwon, Glen S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896148/
https://ncbi.nlm.nih.gov/pubmed/21630670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp2000549
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