Injection of AAV2-BMP2 and AAV2-TIMP1 into the nucleus pulposus slows the course of intervertebral disc degeneration in an in vivo rabbit model

BACKGROUND CONTEXT: Intervertebral disc degeneration (IDD) is a common cause of back pain. Patients who fail conservative management may face the morbidity of surgery. Alternative treatment modalities could have a significant impact on disease progression and patients’ quality of life. PURPOSE: To d...

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發表在:Spine J
Main Authors: Leckie, Steven K., Bechara, Bernard P., Hartman, Robert A., Sowa, Gwendolyn A., Woods, Barrett I., Coelho, Joao P., Witt, William T., Dong, Qing D., Bowman, Brent W., Bell, Kevin M., Vo, Nam V., Wang, Bing, Kang, James D.
格式: Artigo
語言:Inglês
出版: 2011
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896143/
https://ncbi.nlm.nih.gov/pubmed/22023960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.spinee.2011.09.011
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