Injection of AAV2-BMP2 and AAV2-TIMP1 into the nucleus pulposus slows the course of intervertebral disc degeneration in an in vivo rabbit model

BACKGROUND CONTEXT: Intervertebral disc degeneration (IDD) is a common cause of back pain. Patients who fail conservative management may face the morbidity of surgery. Alternative treatment modalities could have a significant impact on disease progression and patients’ quality of life. PURPOSE: To d...

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Detalhes bibliográficos
Publicado no:Spine J
Main Authors: Leckie, Steven K., Bechara, Bernard P., Hartman, Robert A., Sowa, Gwendolyn A., Woods, Barrett I., Coelho, Joao P., Witt, William T., Dong, Qing D., Bowman, Brent W., Bell, Kevin M., Vo, Nam V., Wang, Bing, Kang, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896143/
https://ncbi.nlm.nih.gov/pubmed/22023960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.spinee.2011.09.011
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