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Vagus nerve stimulation mitigates intrinsic cardiac neuronal remodeling and cardiac hypertrophy induced by chronic pressure overload in guinea pig

Our objective was to determine whether chronic vagus nerve stimulation (VNS) mitigates pressure overload (PO)-induced remodeling of the cardioneural interface. Guinea pigs (n = 48) were randomized to right or left cervical vagus (RCV or LCV) implant. After 2 wk, chronic left ventricular PO was induc...

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Bibliografski detalji
Izdano u:Am J Physiol Heart Circ Physiol
Glavni autori: Beaumont, Eric, Wright, Gary L., Southerland, Elizabeth M., Li, Ying, Chui, Ray, KenKnight, Bruce H., Armour, J. Andrew, Ardell, Jeffrey L.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2016
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895835/
https://ncbi.nlm.nih.gov/pubmed/26993230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00939.2015
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