Vagus nerve stimulation mitigates intrinsic cardiac neuronal remodeling and cardiac hypertrophy induced by chronic pressure overload in guinea pig

Our objective was to determine whether chronic vagus nerve stimulation (VNS) mitigates pressure overload (PO)-induced remodeling of the cardioneural interface. Guinea pigs (n = 48) were randomized to right or left cervical vagus (RCV or LCV) implant. After 2 wk, chronic left ventricular PO was induc...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Beaumont, Eric, Wright, Gary L., Southerland, Elizabeth M., Li, Ying, Chui, Ray, KenKnight, Bruce H., Armour, J. Andrew, Ardell, Jeffrey L.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2016
Matèries:
Cardiovascular Neurohormonal Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895835/
https://ncbi.nlm.nih.gov/pubmed/26993230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00939.2015
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