Vagus nerve stimulation mitigates intrinsic cardiac neuronal remodeling and cardiac hypertrophy induced by chronic pressure overload in guinea pig

Our objective was to determine whether chronic vagus nerve stimulation (VNS) mitigates pressure overload (PO)-induced remodeling of the cardioneural interface. Guinea pigs (n = 48) were randomized to right or left cervical vagus (RCV or LCV) implant. After 2 wk, chronic left ventricular PO was induc...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Beaumont, Eric, Wright, Gary L., Southerland, Elizabeth M., Li, Ying, Chui, Ray, KenKnight, Bruce H., Armour, J. Andrew, Ardell, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Cardiovascular Neurohormonal Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895835/
https://ncbi.nlm.nih.gov/pubmed/26993230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00939.2015
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