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Pre-40S ribosome biogenesis factor Tsr1 is an inactive structural mimic of translational GTPases

Budding yeast Tsr1 is a ribosome biogenesis factor with sequence similarity to GTPases, which is essential for cytoplasmic steps in 40S subunit maturation. Here we present the crystal structure of Tsr1 at 3.6 Å. Tsr1 has a similar domain architecture to translational GTPases such as EF-Tu and the se...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: McCaughan, Urszula M., Jayachandran, Uma, Shchepachev, Vadim, Chen, Zhuo Angel, Rappsilber, Juri, Tollervey, David, Cook, Atlanta G.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895721/
https://ncbi.nlm.nih.gov/pubmed/27250689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11789
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