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Power estimation and sample size determination for replication studies of genome-wide association studies

BACKGROUND: Replication study is a commonly used verification method to filter out false positives in genome-wide association studies (GWAS). If an association can be confirmed in a replication study, it will have a high confidence to be true positive. To design a replication study, traditional appr...

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Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Jiang, Wei, Yu, Weichuan
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895704/
https://ncbi.nlm.nih.gov/pubmed/26818952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2296-4
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