Biopterin Status in Dogs with Myxomatous Mitral Valve Disease is Associated with Disease Severity and Cardiovascular Risk Factors

BACKGROUND: Endothelial dysfunction (ED) has been suggested to be associated with myxomatous mitral valve disease (MMVD) in dogs. Tetrahydrobiopterin (BH4) is an important cofactor for production of the endothelium‐derived vasodilator nitric oxide (NO). Under conditions of oxidative stress, BH4 is o...

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Vydáno v:J Vet Intern Med
Hlavní autoři: Reimann, M.J., Häggström, J., Mortensen, A., Lykkesfeldt, J., Møller, J.E., Falk, T., Olsen, L.H.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895593/
https://ncbi.nlm.nih.gov/pubmed/25274442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvim.12425
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