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Biopterin Status in Dogs with Myxomatous Mitral Valve Disease is Associated with Disease Severity and Cardiovascular Risk Factors

BACKGROUND: Endothelial dysfunction (ED) has been suggested to be associated with myxomatous mitral valve disease (MMVD) in dogs. Tetrahydrobiopterin (BH4) is an important cofactor for production of the endothelium‐derived vasodilator nitric oxide (NO). Under conditions of oxidative stress, BH4 is o...

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Bibliografske podrobnosti
izdano v:J Vet Intern Med
Main Authors: Reimann, M.J., Häggström, J., Mortensen, A., Lykkesfeldt, J., Møller, J.E., Falk, T., Olsen, L.H.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895593/
https://ncbi.nlm.nih.gov/pubmed/25274442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvim.12425
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