Biopterin Status in Dogs with Myxomatous Mitral Valve Disease is Associated with Disease Severity and Cardiovascular Risk Factors

BACKGROUND: Endothelial dysfunction (ED) has been suggested to be associated with myxomatous mitral valve disease (MMVD) in dogs. Tetrahydrobiopterin (BH4) is an important cofactor for production of the endothelium‐derived vasodilator nitric oxide (NO). Under conditions of oxidative stress, BH4 is o...

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Détails bibliographiques
Publié dans:J Vet Intern Med
Auteurs principaux: Reimann, M.J., Häggström, J., Mortensen, A., Lykkesfeldt, J., Møller, J.E., Falk, T., Olsen, L.H.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2014
Sujets:
Standard Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895593/
https://ncbi.nlm.nih.gov/pubmed/25274442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvim.12425
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