Stimulation of superoxide production increases fungicidal action of miconazole against Candida albicans biofilms

We performed a whole-transcriptome analysis of miconazole-treated Candida albicans biofilms, using RNA-sequencing. Our aim was to identify molecular pathways employed by biofilm cells of this pathogen to resist action of the commonly used antifungal miconazole. As expected, genes involved in sterol...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: De Cremer, Kaat, De Brucker, Katrijn, Staes, Ines, Peeters, Annelies, Van den Driessche, Freija, Coenye, Tom, Cammue, Bruno P. A., Thevissen, Karin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895440/
https://ncbi.nlm.nih.gov/pubmed/27272719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27463
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