Identification of Fungicidal 2,6-Disubstituted Quinolines with Activity against Candida Biofilms

We have identified two subseries of 2,6-disubstituted quinolines, consisting of 6-amide and 6-urea derivatives, which are characterized by fungicidal activity against Candida albicans with minimal fungicidal concentration (MFC) values < 15 µM. The 6-amide derivatives displayed the highest fungici...

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Bibliographic Details
Published in:Molecules
Main Authors: Delattin, Nicolas, Bardiot, Dorothée, Marchand, Arnaud, Chaltin, Patrick, De Brucker, Katrijn, Cammue, Bruno P. A., Thevissen, Karin
Format: Artigo
Language:Inglês
Published: MDPI 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268363/
https://ncbi.nlm.nih.gov/pubmed/23079495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules171012243
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