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A simple two-state protein unfolds mechanically via multiple heterogeneous pathways at single-molecule resolution

A major drive in protein folding has been to develop experimental technologies to resolve the myriads of microscopic pathways and complex mechanisms that purportedly underlie simple two-state folding behaviour. This is key for cross-validating predictions from theory and modern computer simulations....

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Schönfelder, Jörg, Perez-Jimenez, Raul, Muñoz, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895439/
https://ncbi.nlm.nih.gov/pubmed/27248054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11777
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