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Heterogeneous Nuclear Ribonucleoprotein L is required for the survival and functional integrity of murine hematopoietic stem cells

The proliferation and survival of hematopoietic stem cells (HSCs) has to be strictly coordinated to ensure the timely production of all blood cells. Here we report that the splice factor and RNA binding protein hnRNP L (heterogeneous nuclear ribonucleoprotein L) is required for hematopoiesis, since...

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發表在:Sci Rep
Main Authors: Gaudreau, Marie-Claude, Grapton, Damien, Helness, Anne, Vadnais, Charles, Fraszczak, Jennifer, Shooshtarizadeh, Peiman, Wilhelm, Brian, Robert, François, Heyd, Florian, Möröy, Tarik
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895350/
https://ncbi.nlm.nih.gov/pubmed/27271479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27379
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