Significant decrease in peripheral regulatory B cells is an immunopathogenic feature of dermatomyositis

Regulatory B cells (Bregs) are critical in maintaining self-tolerance. Their role in dermatomyositis (DM), an autoimmune disease characterized by inappropriate regulation of hyperactivated B and T cells, has not been clearly defined. In the current study, we performed flow cytometry analysis of stud...

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Pubblicato in:Sci Rep
Autori principali: Li, Wenli, Tian, Xiaolan, Lu, Xin, Peng, Qinglin, Shu, Xiaoming, Yang, Hanbo, Li, Yuanli, Wang, Yan, Zhang, Xuezhi, Liu, Qingyan, Wang, Guochun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895339/
https://ncbi.nlm.nih.gov/pubmed/27270362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27479
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