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Identifying micro-inversions using high-throughput sequencing reads

BACKGROUND: The identification of inversions of DNA segments shorter than read length (e.g., 100 bp), defined as micro-inversions (MIs), remains challenging for next-generation sequencing reads. It is acknowledged that MIs are important genomic variation and may play roles in causing genetic disease...

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: He, Feifei, Li, Yang, Tang, Yu-Hang, Ma, Jian, Zhu, Huaiqiu
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895285/
https://ncbi.nlm.nih.gov/pubmed/26818118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2305-7
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