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A Bayesian approach for estimating allele-specific expression from RNA-Seq data with diploid genomes
BACKGROUND: RNA-sequencing (RNA-Seq) has become a popular tool for transcriptome profiling in mammals. However, accurate estimation of allele-specific expression (ASE) based on alignments of reads to the reference genome is challenging, because it contains only one allele on a mosaic haploid genome....
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| Vydáno v: | BMC Genomics |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4895278/ https://ncbi.nlm.nih.gov/pubmed/26818838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2295-5 |
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