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HLA-VBSeq: accurate HLA typing at full resolution from whole-genome sequencing data

BACKGROUND: Human leucocyte antigen (HLA) genes play an important role in determining the outcome of organ transplantation and are linked to many human diseases. Because of the diversity and polymorphisms of HLA loci, HLA typing at high resolution is challenging even with whole-genome sequencing dat...

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Detalles Bibliográficos
Publicado en:BMC Genomics
Main Authors: Nariai, Naoki, Kojima, Kaname, Saito, Sakae, Mimori, Takahiro, Sato, Yukuto, Kawai, Yosuke, Yamaguchi-Kabata, Yumi, Yasuda, Jun, Nagasaki, Masao
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331721/
https://ncbi.nlm.nih.gov/pubmed/25708870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S2-S7
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