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Nuclear transport of paxillin depends on focal adhesion dynamics and FAT domains

The nuclear transport of paxillin appears to be crucial for paxillin function but the mechanism of transport remains unclear. Here, we show that the nuclear transport of paxillin is regulated by focal adhesion turnover and the presence of FAT domains. Focal adhesion turnover was controlled using tri...

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Dades bibliogràfiques
Publicat a:J Cell Sci
Autors principals: Sathe, Aneesh R., Shivashankar, G. V., Sheetz, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895192/
https://ncbi.nlm.nih.gov/pubmed/27068537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.172643
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