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Nuclear transport of paxillin depends on focal adhesion dynamics and FAT domains

The nuclear transport of paxillin appears to be crucial for paxillin function but the mechanism of transport remains unclear. Here, we show that the nuclear transport of paxillin is regulated by focal adhesion turnover and the presence of FAT domains. Focal adhesion turnover was controlled using tri...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Sathe, Aneesh R., Shivashankar, G. V., Sheetz, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895192/
https://ncbi.nlm.nih.gov/pubmed/27068537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.172643
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