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A method to rapidly create protein aggregates in living cells

The accumulation of protein aggregates is a common pathological hallmark of many neurodegenerative diseases. However, we do not fully understand how aggregates are formed or the complex network of chaperones, proteasomes and other regulatory factors involved in their clearance. Here, we report a che...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Miyazaki, Yusuke, Mizumoto, Kota, Dey, Gautam, Kudo, Takamasa, Perrino, John, Chen, Ling-chun, Meyer, Tobias, Wandless, Thomas J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894968/
https://ncbi.nlm.nih.gov/pubmed/27229621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11689
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