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Choreographing the Double Strand Break Response: Ubiquitin and SUMO Control of Nuclear Architecture

The cellular response to DNA double strand breaks (DSBs) is a multifaceted signaling program that centers on post-translational modifications including phosphorylation, ubiquitylation and SUMOylation. In this review we discuss how ubiquitin and SUMO orchestrate the recognition of DSBs and explore ho...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Harding, Shane M., Greenberg, Roger A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894868/
https://ncbi.nlm.nih.gov/pubmed/27375678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00103
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