A Large-Scale Investigation of Hypoxia-Preconditioned Allogeneic Mesenchymal Stem Cells for Myocardial Repair in Nonhuman Primates: Paracrine Activity Without Remuscularization

RATIONALE: The effectiveness of transplanted bone marrow mesenchymal stem cells (MSCs) for cardiac repair has been limited; thus, strategies for optimizing stem-cell–based myocardial therapy are needed. OBJECTIVE: The present study was designed to test our central hypothesis that hypoxia-preconditio...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Hu, Xinyang, Xu, Yinchuan, Zhong, Zhiwei, Wu, Yan, Zhao, Jing, Wang, Yingchao, Cheng, Haifeng, Kong, Minjian, Zhang, Fengjiang, Chen, Qi, Sun, Jianzhong, Li, Qian, Jin, Jing, Li, Qingju, Chen, Lihong, Wang, Chen, Zhan, Hongwei, Fan, Youqi, Yang, Qian, Yu, Lei, Wu, Rongrong, Liang, Jie, Zhu, Jinyun, Wang, Ya, Jin, Yiping, Lin, Yifan, Yang, Fan, Jia, Liangliang, Zhu, Wei, Chen, Jinghai, Yu, Hong, Zhang, Jianyi, Wang, Jian’an
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
Assuntos:
Integrative Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894788/
https://ncbi.nlm.nih.gov/pubmed/26838793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.307516
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