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Heparanase Released From Mesenchymal Stem Cells Activates Integrin beta1/HIF-2alpha/Flk-1 Signaling and Promotes Endothelial Cell Migration and Angiogenesis

Heparanase plays important roles in tumor angiogenesis. Our previous study demonstrated that hypoxic preconditioning (HPC) enhanced the angiogenic and therapeutic effects of mesenchymal stem cells (MSCs), effects that were paralleled by enhanced heparanase expression. This study was designed to eluc...

詳細記述

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書誌詳細
出版年:Stem Cells
主要な著者: Hu, Xinyang, Zhang, Ling, Jin, Jing, Zhu, Wei, Xu, Yinchuan, Wu, Yan, Wang, Yingchao, Chen, Han, Webster, Keith A., Chen, Huiqiang, Yu, Hong, Wang, Jian’an
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108061/
https://ncbi.nlm.nih.gov/pubmed/25754303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1995
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