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Impact on Life Expectancy of Withdrawing Thiopurines in Patients with Crohn’s Disease in Sustained Clinical Remission: A Lifetime Risk-Benefit Analysis

OBJECTIVE: Long-term treatment with thiopurines is associated with a decreased risk of Crohn’s disease (CD) flare but an increased risk of various cancers depending on gender, age, and presence of extensive colitis. We evaluated risks and benefits of withdrawing thiopurines in patients with CD in pr...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Kirchgesner, Julien, Beaugerie, Laurent, Carrat, Fabrice, Sokol, Harry, Cosnes, Jacques, Schwarzinger, Michaël
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894633/
https://ncbi.nlm.nih.gov/pubmed/27271176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157191
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