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Impact on Life Expectancy of Withdrawing Thiopurines in Patients with Crohn’s Disease in Sustained Clinical Remission: A Lifetime Risk-Benefit Analysis

OBJECTIVE: Long-term treatment with thiopurines is associated with a decreased risk of Crohn’s disease (CD) flare but an increased risk of various cancers depending on gender, age, and presence of extensive colitis. We evaluated risks and benefits of withdrawing thiopurines in patients with CD in pr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kirchgesner, Julien, Beaugerie, Laurent, Carrat, Fabrice, Sokol, Harry, Cosnes, Jacques, Schwarzinger, Michaël
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894633/
https://ncbi.nlm.nih.gov/pubmed/27271176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157191
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