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Selective Translation of Leaderless mRNAs by Specialized Ribosomes Generated by MazF in Escherichia coli

Escherichia coli (E. coli) mazEF is a stress-induced toxin-antitoxin (TA) module. The toxin MazF is an endoribonuclease that cleaves single-stranded mRNAs at ACA sequences. Here, we show that MazF cleaves at ACA sites at or closely upstream of the AUG start codon of some specific mRNAs and thereby g...

詳細記述

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書誌詳細
出版年:Cell
主要な著者: Vesper, Oliver, Amitai, Shahar, Belitsky, Maria, Byrgazov, Konstantin, Kaberdina, Anna Chao, Engelberg-Kulka, Hanna, Moll, Isabella
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894548/
https://ncbi.nlm.nih.gov/pubmed/21944167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.07.047
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