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Selective Translation of Leaderless mRNAs by Specialized Ribosomes Generated by MazF in Escherichia coli

Escherichia coli (E. coli) mazEF is a stress-induced toxin-antitoxin (TA) module. The toxin MazF is an endoribonuclease that cleaves single-stranded mRNAs at ACA sequences. Here, we show that MazF cleaves at ACA sites at or closely upstream of the AUG start codon of some specific mRNAs and thereby g...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Vesper, Oliver, Amitai, Shahar, Belitsky, Maria, Byrgazov, Konstantin, Kaberdina, Anna Chao, Engelberg-Kulka, Hanna, Moll, Isabella
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894548/
https://ncbi.nlm.nih.gov/pubmed/21944167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.07.047
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