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The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria
The detection of microbes and initiation of an innate immune response occur through pattern recognition receptors (PRRs), which are critical for the production of inflammatory cytokines and activation of the cellular microbicidal machinery. In particular, the production of reactive oxygen species (R...
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| Pubblicato in: | Sci Signal |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4894535/ https://ncbi.nlm.nih.gov/pubmed/26838550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aac6250 |
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