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The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria

The detection of microbes and initiation of an innate immune response occur through pattern recognition receptors (PRRs), which are critical for the production of inflammatory cytokines and activation of the cellular microbicidal machinery. In particular, the production of reactive oxygen species (R...

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Bibliografische gegevens
Gepubliceerd in:Sci Signal
Hoofdauteurs: Billings, Emily A., Lee, Chang Sup, Owen, Katherine A., D’Souza, Ryan S., Ravichandran, Kodi S., Casanova, James E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894535/
https://ncbi.nlm.nih.gov/pubmed/26838550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aac6250
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