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The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria

The detection of microbes and initiation of an innate immune response occur through pattern recognition receptors (PRRs), which are critical for the production of inflammatory cytokines and activation of the cellular microbicidal machinery. In particular, the production of reactive oxygen species (R...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Billings, Emily A., Lee, Chang Sup, Owen, Katherine A., D’Souza, Ryan S., Ravichandran, Kodi S., Casanova, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894535/
https://ncbi.nlm.nih.gov/pubmed/26838550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aac6250
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