Liver-specific ablation of KRAB Associated Protein 1 in mice leads to male-predominant hepatosteatosis and development of liver adenoma

The liver is characterized by sexually dimorphic gene expression translating into sex-specific differences in lipid, drug, steroid hormone and xenobiotic metabolism, with distinct responses of males and females to environmental challenges. Here, we investigated the role of the KRAB-associated protei...

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Publicado en:Hepatology
Autores principales: Bojkowska, Karolina, Kapopoulou, Adamandia, Santoni de Sio, Francesca, Aloisio, Fabio, Cassano, Marco, Zangger, Nadine, Offner, Sandra, Cartoni, Cristina, Thomas, Charles, Quenneville, Simon, Johnsson, Kai, Trono, Didier
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894457/
https://ncbi.nlm.nih.gov/pubmed/22684873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25767
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