Wordt geladen...
The structural basis of an NADP(+)-independent dithiol oxidase in FK228 biosynthesis
The disulfide bond is unusual in natural products and critical for thermal stability, cell permeability and bioactivity. DepH from Chromobacterium violaceum No. 968 is an FAD-dependent enzyme responsible for catalyzing the disulfide bond formation of FK228, an anticancer prodrug approved for the tre...
Bewaard in:
| Gepubliceerd in: | Sci Rep |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2014
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4894451/ https://ncbi.nlm.nih.gov/pubmed/24553401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04145 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|