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Subverting the B7-H1/PD-1 Pathway in Advanced Melanoma and Kidney Cancer
Ligands for inhibitory immune receptors on T cells may be constitutively expressed on tumor cells or host cells in tumor microenvironment as a consequence of adaptive immunity. Programmed death 1 (PD-1) is 1 such receptor on T cells, which functions as a negative regulator of T cell activity. Tumors...
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| Publicado no: | Cancer J |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4894310/ https://ncbi.nlm.nih.gov/pubmed/25098288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000055 |
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