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Harnessing the PD-1 Pathway in Renal Cell Carcinoma: Current Evidence and Future Directions
Programmed cell death-1 (PD-1) is a recognized immune checkpoint. It is frequently upregulated on the T cells that infiltrate tumors, providing an inhibitory signal, which may facilitate immune escape. Blocking antibodies have been developed to interrupt the interaction of PD-1 with its ligands PD-L...
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| Publicado no: | BioDrugs |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4888066/ https://ncbi.nlm.nih.gov/pubmed/25445176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40259-014-0111-4 |
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