TWIST1 polymorphisms predict survival in patients with metastatic colorectal cancer receiving first-line bevacizumab plus oxaliplatin-based chemotherapy

The epithelial-mesenchymal transition (EMT) is an important mechanism of resistance to angiogenesis inhibition. The ability of EMT pathway genetic variants to predict the efficacy of anti-angiogenic therapy is unknown. We analyzed associations between functional single nucleotide polymorphisms (SNPs...

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Publié dans:Mol Cancer Ther
Auteurs principaux: Matsusaka, Satoshi, Zhang, Wu, Cao, Shu, Hanna, Diana L., Sunakawa, Yu, Sebio, Ana, Ueno, Masashi, Yang, Dongyun, Ning, Yan, Parekh, Anish, Okazaki, Satoshi, Berger, Martin D., Ichikawa, Wataru, Mizunuma, Nobuyuki, Lenz, Heinz-Josef.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893985/
https://ncbi.nlm.nih.gov/pubmed/26983880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0751
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