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Amino Acid Auxotrophy as Immunological Control Nodes

Cells of the immune system are auxotrophs for most amino acids, including non-essential ones. Arginine and tryptophan are used within the regulatory immune networks to control proliferation and function through pathways that deplete the amino acid, or create regulatory molecules such as nitric oxide...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Immunol
1. Verfasser: Murray, Peter J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893777/
https://ncbi.nlm.nih.gov/pubmed/26784254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3323
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