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Amino Acid Auxotrophy as Immunological Control Nodes

Cells of the immune system are auxotrophs for most amino acids, including non-essential ones. Arginine and tryptophan are used within the regulatory immune networks to control proliferation and function through pathways that deplete the amino acid, or create regulatory molecules such as nitric oxide...

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Bibliographic Details
Published in:Nat Immunol
Main Author: Murray, Peter J.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893777/
https://ncbi.nlm.nih.gov/pubmed/26784254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3323
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