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CENP-C directs a structural transition of the CENP-A nucleosome mainly through sliding of DNA gyres

The histone H3 variant, CENP-A, is incorporated into nucleosomes that mark centromere location. We recently reported that CENP-A confers an altered nucleosome shape relative to its counterparts containing conventional H3. Using a single molecule fluorescence resonance energy transfer (FRET) approach...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Falk, Samantha J., Lee, Jaehyoun, Sekulic, Nikolina, Sennett, Michael A., Lee, Tae-Hee, Black, Ben E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893769/
https://ncbi.nlm.nih.gov/pubmed/26878239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3175
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