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Protective effect of etanercept, an inhibitor of tumor necrosis factor-α, in a rat model of retinal ischemia

BACKGROUND: To assess the neuroprotective effect of etanercept (Enbrel®) which is a commercialized Tumor necrosis factor-α (TNF-α) inhibitor on axonal injury in an animal model of acute ischemia. METHODS: Acute ischemia was induced by intraocular pressure elevation in 36 rats. The treatment groups u...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Ophthalmol
Hauptverfasser: Bae, Hyoung Won, Lee, Naeun, Seong, Gong Je, Rho, Seungsoo, Hong, Samin, Kim, Chan Yun
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893298/
https://ncbi.nlm.nih.gov/pubmed/27259948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12886-016-0262-9
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