Plasma Trimethylamine N-oxide, a Gut Microbe-Generated Phosphatidylcholine Metabolite, is Associated with Atherosclerotic Burden

BACKGROUND: Trimethylamine N-oxide (TMAO), a gut microbiota metabolite from dietary phosphatidylcholine, has mechanistic links to atherosclerotic coronary artery disease (CAD) pathogenesis and is associated with adverse outcomes. OBJECTIVES: We examined the relationship between plasma TMAO levels an...

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Veröffentlicht in:J Am Coll Cardiol
Hauptverfasser: Senthong, Vichai, Li, XinMin S., Hudec, Timothy, Coughlin, John, Wu, Yuping, Levison, Bruce, Wang, Zeneng, Hazen, Stanley L., Wilson Tang, W. H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893167/
https://ncbi.nlm.nih.gov/pubmed/27256833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2016.03.546
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