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Neutrophil microvesicles resolve gout by inhibiting C5a-mediated priming of the inflammasome
OBJECTIVES: Gout is a highly inflammatory but self-limiting joint disease induced by the precipitation of monosodium urate (MSU) crystals. While it is well established that inflammasome activation by MSU mediates acute inflammation, little is known about the mechanism controlling its spontaneous res...
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| Publicado no: | Ann Rheum Dis |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4893114/ https://ncbi.nlm.nih.gov/pubmed/26245757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2015-207338 |
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