Role of EGF Receptor Ligands in TCDD-induced EGFR Down-regulation and Cellular Proliferation

In cultures of normal human epidermal keratinocytes (NHEKs), 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces the expression of the epidermal growth factor receptor ligands transforming growth factor-α (TGF-α) and epiregulin (EREG). TCDD also down-regulates EGF receptors (EGFR), suggesting that de...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chem Biol Interact
Prif Awduron: Campion, Christina M, Carrion, Sandra Leon, Mamidanna, Gayatri, Sutter, Carrie Hayes, Sutter, Thomas R, Cole, Judith A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892999/
https://ncbi.nlm.nih.gov/pubmed/27117977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2016.04.031
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg