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Disposition Kinetics and Metabolism of Nicotine and Cotinine in African American smokers: Impact of CYP2A6 Genetic Variation and Enzymatic Activity
OBJECTIVE: The rate of nicotine metabolism, determined primarily by CYP2A6 activity, influences tobacco dependence and smoking-induced disease risk. The prevalence of CYP2A6 gene variants differs by race, with greater numbers in African American (AA) compared to Caucasians. We studied nicotine dispo...
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| Publicado en: | Pharmacogenet Genomics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4892970/ https://ncbi.nlm.nih.gov/pubmed/27035242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000222 |
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