Myeloid deletion of SIRT1 suppresses collagen-induced arthritis in mice by modulating dendritic cell maturation

The type III histone deacetylase silent information regulator 1 (SIRT1) is an enzyme that is critical for the modulation of immune and inflammatory responses. However, the data on its role in rheumatoid arthritis (RA) are limited and controversial. To better understand how SIRT1 regulates adaptive i...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Woo, Seong Ji, Lee, Sang-Myeong, Lim, Hye Song, Hah, Young-Sool, Jung, In Duk, Park, Yeong-Min, Kim, Hyun-Ok, Cheon, Yun-Hong, Jeon, Min-Gyu, Jang, Kyu Yun, Kim, Kyeong Min, Park, Byung-Hyun, Lee, Sang-Il
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892877/
https://ncbi.nlm.nih.gov/pubmed/26987484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2015.124
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