Cholesterol biosynthesis inhibitor RO 48-8071 suppresses growth of hormone-dependent and castration-resistant prostate cancer cells

Standard treatment for primary prostate cancer includes systemic exposure to chemotherapeutic drugs that target androgen receptor or antihormone therapy (chemical castration); however, drug-resistant cancer cells generally emerge during treatment, limiting the continued use of systemic chemotherapy....

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Liang, Yayun, Mafuvadze, Benford, Aebi, Johannes D, Hyder, Salman M
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892832/
https://ncbi.nlm.nih.gov/pubmed/27313468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S105725
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