MicroRNAs targeting TGFβ signalling underlie the regulatory T cell defect in multiple sclerosis

Transforming growth factor beta (TGFβ) signalling is critical for regulatory T cell development and function, and regulatory T cell dysregulation is a common observation in autoimmune diseases, including multiple sclerosis. In a comprehensive miRNA profiling study of patients with multiple sclerosis...

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Bibliographic Details
Published in:Brain
Main Authors: Severin, Mary E., Lee, Priscilla W., Liu, Yue, Selhorst, Amanda J., Gormley, Matthew G., Pei, Wei, Yang, Yuhong, Guerau-de-Arellano, Mireia, Racke, Michael K., Lovett-Racke, Amy E.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892757/
https://ncbi.nlm.nih.gov/pubmed/27190026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aww084
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