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Graded effects of unregulated smooth muscle myosin on intestinal architecture, intestinal motility and vascular function in zebrafish

Smooth muscle contraction is controlled by the regulated activity of the myosin heavy chain ATPase (Myh11). Myh11 mutations have diverse effects in the cardiovascular, digestive and genitourinary systems in humans and animal models. We previously reported a recessive missense mutation, meltdown (mlt...

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Détails bibliographiques
Publié dans:Dis Model Mech
Auteurs principaux: Abrams, Joshua, Einhorn, Zev, Seiler, Christoph, Zong, Alan B., Sweeney, H. Lee, Pack, Michael
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892660/
https://ncbi.nlm.nih.gov/pubmed/26893369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.023309
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