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Graded effects of unregulated smooth muscle myosin on intestinal architecture, intestinal motility and vascular function in zebrafish

Smooth muscle contraction is controlled by the regulated activity of the myosin heavy chain ATPase (Myh11). Myh11 mutations have diverse effects in the cardiovascular, digestive and genitourinary systems in humans and animal models. We previously reported a recessive missense mutation, meltdown (mlt...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Abrams, Joshua, Einhorn, Zev, Seiler, Christoph, Zong, Alan B., Sweeney, H. Lee, Pack, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892660/
https://ncbi.nlm.nih.gov/pubmed/26893369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.023309
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