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sFlt Multivalent Conjugates Inhibit Angiogenesis and Improve Half-Life In Vivo
Current anti-VEGF drugs for patients with diabetic retinopathy suffer from short residence time in the vitreous of the eye. In order to maintain biologically effective doses of drug for inhibiting retinal neovascularization, patients are required to receive regular monthly injections of drug, which...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4892585/ https://ncbi.nlm.nih.gov/pubmed/27257918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155990 |
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