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Modulation of natural killer cell functions by interactions between 2B4 and CD48 in cis and in trans
SLAM-related receptors (SRRs) are important modulators of immune cell function. While most SRRs are homophilic, 2B4 (CD244) interacts with CD48, a GPI-anchored protein expressed on many haematopoietic cells. Here we show that natural killer (NK) cell-expressed 2B4 not only binds in trans to CD48 on...
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| Publicado en: | Open Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Royal Society
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4892432/ https://ncbi.nlm.nih.gov/pubmed/27249817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160010 |
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