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Eosinophils contribute to intestinal inflammation via chemoattractant receptor-homologous molecule expressed on Th2 cells, CRTH2, in experimental Crohn’s disease
BACKGROUND AND AIMS: Prostaglandin (PG) D(2) activates two receptors, DP and CRTH2. Antagonism of CRTH2 has been shown to promote anti-allergic and anti-inflammatory effects. We investigated whether CRTH2 may play a role in Crohn’s disease (CD) focusing on eosinophils, which are largely present in t...
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| 出版年: | J Crohns Colitis |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4892354/ https://ncbi.nlm.nih.gov/pubmed/26928963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjw061 |
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