Low Oxygen Modulates Multiple Signaling Pathways, Increasing Self-Renewal, While Decreasing Differentiation, Senescence, and Apoptosis in Stromal MIAMI Cells

Human bone marrow multipotent mesenchymal stromal cell (hMSC) number decreases with aging. Subpopulations of hMSCs can differentiate into cells found in bone, vasculature, cartilage, gut, and other tissues and participate in their repair. Maintaining throughout adult life such cell subpopulations sh...

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Dettagli Bibliografici
Pubblicato in:Stem Cells Dev
Autori principali: Rios, Carmen, D'Ippolito, Gianluca, Curtis, Kevin M., Delcroix, Gaëtan J.-R., Gomez, Lourdes A., El Hokayem, Jimmy, Rieger, Megan, Parrondo, Ricardo, de las Pozas, Alicia, Perez-Stable, Carlos, Howard, Guy A., Schiller, Paul C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2016
Soggetti:
Original Research Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892221/
https://ncbi.nlm.nih.gov/pubmed/27059084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0362
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